• There are two good reasons to take care of your teeth and want to smile again:

    A functional reason related to the correct chewing and consequent digestion and absorption of nutrients contained in food, posture and body health;

    2. A psychological reason, as having healthy teeth improves aesthetics, increases well-being and self-esteem.


  • Bone loss can be caused by several factors. A typical example is gum inflammation due to bacterial plaque which, if not removed with proper oral hygiene, affects the bone.

    In other cases, following a tooth extraction, bone thickness could be reduced. Even the use of removable dental prostheses that does not adequately stress the bone tissue, produces its resorption.

  • Other causes of bone loss can be due to trauma or pathologies such as peri-implantitis, with consequences such as: Loss of tooth or implant, Defects in chewing, Inability to insert the dental implant, Instability of the implant, Alteration of phonetics, Decreased self-esteem.
  • Regardless of the causes of bone loss, what matters is to proceed to a timely restoration of bone volume, to ensure a fast functional recovery of chewing and ensure the long-term stability of teeth and implants, as well as improve the aesthetics of teeth and gums. Human bone can regenerate, but in some conditions, such as when a large amount of bone tissue is missing, our body needs help.

What are biomaterials and what are they used for?

  • Biomaterials are inert bone grafts, used for repairing and regenerating bone tissue in the sinus or jaw. They are used in various fields of medicine, but mainly in orthopedic and dentistry. There are two main macro-categories into which biomaterials can be divided: bone substitutes and emembranes capable of protecting the bone graft in the area of intervention.

    Bone grafts, according to their origin, are divided into:

    AUTOLOGOUS Bone material taken from the patient themselves, from the sinus and jaw or from areas outside the oral cavity;

    HOMOLOGOUS Provided by regional and national musculoskeletal tissue banks, identified and authorized by the Ministry of Health;

    HETEROLOGOUS Of animal origin (bovine, equine, porcine) either synthetic, or chemical (called synthetic or non-absorbable.

  • In case of bone deficiency it is advisable to use RE-BONE® bovine graft. RE-BONE® is positioned in the area to be restored allowing the positive outcome of the intervention. In addition, RE-BONE® is resorbable, i.e. it retreats over time, letting the patient's body progressively rebuild its internal tissue.

Can animal biomaterials transmit infections or diseases to humans?

  • Sometimes the risk is present. However, RE-BONE®, the resorbable biomaterial of bovine origin UBGEN®, increases the level of safety to almost 100% because:

    • The animals used are less than 24 months old to rule out the presence of bovine spongiform encephalopathy (mad cow disease).

    • It is the only cattle treated at low temperature (thanks to the Thermagen process) that allows to make it almost completely resorbable.

    • Il paziente, dopo poco tempo, svilupperà osso proprio e non avrà materiale residuo animale all’interno del proprio corpo;

    • The patient, after a short time, will develop their own bone and will have no animal residue material inside their body.

    • It comes from a 100% Italian supply chain and is subject to strict process control.

    • It has CE certifications from the Italian National Institute of Health.

    • It is also registered and certified in non-EU countries.


  • Despite the characteristic hardness and strength, bone is not a static tissue, but is constantly changing and repaired. This process is called bone remodeling. Every year about 10% of our overall bone mass is renewed. The bone substitute (biomaterial), keeping the bone volume unchanged and ensuring the stability of the implant screws, promotes the process of regeneration and healing of the surgical wound.

How does bone reconstruction contribute to implant stabilization?

  • Following the tooth extraction, near the extractive alveolus, both bone and gum tend to a progressive and natural reduction of their volume. In order to guarantee stability to the implants, it is good to fill the extraction cavities with a biomaterial that will help to maintain the bone volume.


  • It is necessary to adopt appropriate post-operative behaviors to reduce recovery times and minimize the onset of any complications. On the opposite page we list the five main post-operative indications to be adopted after bone regeneration surgery. In case of pain or any doubt, always consult your dentist.

    • Treat any swelling with cold compresses.

    • In case of pain, ask your dentist, if you have not already done so, for an adequate pain reliever.

    • For the first few weeks, during daily oral hygiene procedures, avoid the operated area, use an antibacterial mouthwash and, later, in the area surrounding the wound use only a toothbrush with soft bristles.

    • Avoid coffee, alcohol and cigarettes for 2-3 days after surgery.

    This warning reduces the risk of post-operative bleeding and improves wound healing (smoking and insufficient oral hygiene can have a significant negative impact on the outcome of therapy).

    • Even if the recovery proceeds smoothly, respect the schedule of check-ups set by your dentist.

We certify that the entire range of medical devices described above is CE marked and manufactured in accordance with the requirements of Directive 93/42 / EEC implemented in Italy with the DLGS. n. 46 dated 24-02-97 and subsequent amendments. The company operates in compliance with UNI EN ISO 9001 standards.

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