Several studies suggest that the use of a platelet concentrate, either alone or combined with other surgical techniques, or even as a support to implant devices, improves the final success of operations, significantly increasing patient’s comfort by reducing healing time.

In dentistry, the APG® method is used for:

• Accelerating the healing of surgical wounds;
• Reducing inflammation and post-operative discomfort;
• The surgical treatment of post-extraction alveolus associated with biomaterials;
• Maxillary sinus surgery;
• Periodontal and muco-gingival surgery;
• The surgical treatment of patients with bisphosphonates-induced osteonecrosis.

In all these treatments, the adhesive nature of APG® facilitates the handling of implant material, improving hemostasis and wound closure compared to the traditional technique.

Furthermore, recent studies have shown that the use of platelet-rich plasma increases microvascular proliferation in the early stages of healing, followed by a better osteoblastic activity.

APG® concentrate in cosmetic surgery In the dermis, exposure to UVB rays stimulates collagenase production by fibroblasts present in the skin that degrade collagen. This process causes the alteration of the disposition of the elastic tissue reducing the structural integrity of the dermis, the first cause of wrinkles and loss of skin elasticity.

Since APG® concentrate contains a number of growth factors that regulate skin regeneration, it can induce the synthesis of collagen and other components of the skin by stimulating and activating fibroblasts, thereby encouraging cells to rejuvenate.

It has been shown that the use of APG® concentrate during cosmetic laser treatments increased skin elasticity, the amount of collagen and the number of fibroblasts, demonstrating a better cosmetic result and faster wound healing.

The APG® method is used for:

• Treating forehead wrinkles, wrinkles around the eyes, nasolabial wrinkles, wrinkles on the neck and on the neckline;
• Treating acne scars;
• Toning the skin and reducing sagging skin;
• Treating stretch marks;
• Treating and re-epithelialising skin wounds and ulcers.

In recent years, clinical experience has shown that acute traumatic injuries of the muscles, tendons, and joint capsules significantly benefit from treatment with platelet growth factors, also in relation to the age of patients, the affected area of the body and its degree of functionality.

Young patients and athletes benefit from the use of platelet growth factors by reducing the time of functional damage, guaranteeing a faster recovery.

More specifically, the application of APG® concentrate has proved particularly effective in the treatment of acute and chronic injuries of tendons, osteoarthritis, and epicondylitis.

It was recently found that treatments with platelet concentrate on patients affected by alopecia areata or baldness result in increased hair growth and thickness, as well as an increased number of hair follicles and improved microcapillary angiogenesis.

This treatment has no side effects; it is well tolerated and offers tangible results from the very first use and in a short time, both in terms of reduced hair loss and improved re-growth and thickening of the hair.